Zetaclear is both an oral and topical medication to treat nail fungus. It claims that the oral spray helps to deliver effective ingredients needed to fight fungus into the bloodstream, whereas the topical treatment polishes and smooths the nails as well as softens the skin around the nail bed.  Zetaclear comes in a white box and in two separate purple glass bottles — one in a small spray bottle and the topical solution in a smaller bottle. Interested whether the two-pronged attack of Zetaclear worked, I did some research into the ingredients, price and guarantee.

Zetaclear Ingredients

The ingredients in Zetaclear are FDA approved and clinically tested.

For The Oral Spray, the ingredients are:

  • Antimonium Curdum 200C: Eases sensitivity of the skin beneath your nails
  • Arsenicum Acidum 30C: Treats nail discoloration
  • Sulphur 12X: Fights against and treats ulcers in the nails
  • Nitricum Acidum 30C: Used for pain relief
  • Arbor Vitae: Fights against warts and other related infections
  • Mancinella 30C:  Works against discoloration of the toes

Ingredients in the Topical Clear Nail Solution are:

Almond Oil, Lemongrass Oil, Clove Oil, Vitamin E Oil, Undecyclenic Acid, Clove Oil, Tea Tree Oil, and Jojoba Oil


The Zetaclear oral spray should be sprayed directly into the mouth 2 or 3 times daily.  This will introduce ingredients directly into the bloodstream. The topical solution should be applied directly to the affected area 3 times daily to work effectively. One box of the spray and topical polish should last for 1 month.

It is recommended that pregnant or breastfeeding women should consult with their physicians before using Zetaclear.


If you were to purchase a 1-month supply directly from the Zetaclear website, it would cost $49.95 plus shipping. A 5-month supply of the product was $149.95. However, I was able to find varying prices for a 1-month supply of Zetaclear, including on Amazon.com where it was advertised at just $23.99 plus shipping, a significantly cheaper deal, though without the money back guarantee.

Zetaclear Guarantee

Yes, the official website offers a money back guarantee for purchase direct from the manufacturer.

There were many positive reviews on the company’s website and other websites such as Amazon.com, but keep in mind that results vary from person to person. Common complaints included that the product worked slowly.


This product had an attractive website and packaging, and an interesting two-pronged approach with using a spray and a topical polish. However, the ingredient list included only two fungus-fighting ingredients, which resulted in a slow success rate for the product.


Click here to learn about our Top Nail Fungus Treatment Products.